High dose antipsychotic prescribing

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High-dose antipsychotic medication.

The dopamine hypothesis for the mode of action of antipsychotic drugs has been with us for some 30 years and has, by and large, withstood the test of time. It simply states that antipsychotic drugs owe their therapeutic effects to an ability to block central dopamine receptors. This has given us a working and testable explanation for the effects of these drugs and it has prompted the synthesis ...

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BACKGROUND Clinical guidelines recommend the routine use of a single antipsychotic drug in a standard dose, but prescriptions for high-dose and combined antipsychotics are common in clinical practice. AIMS To evaluate the effectiveness of a quality improvement programme in reducing the prevalence of high-dose and combined antipsychotic prescribing in acute adult in-patient wards in the UK. ...

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Prevalence and Correlates of “High Dose” Antipsychotic Prescribing: Findings from a Hospital Audit

BACKGROUND High dose antipsychotic prescribing is common in psychiatric care, despite a lack of its benefit from research evidence. While several studies have explored the prevalence and factors associated with high dose antipsychotic prescribing, no such report has emanated from a developing country like Nigeria. AIM The aims of this study were to determine the prevalence of high dose prescr...

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ژورنال

عنوان ژورنال: Psychiatric Bulletin

سال: 1997

ISSN: 0955-6036,1472-1473

DOI: 10.1192/pb.21.1.58-c